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Zamaglutenase - Takeda

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Drug Profile

Zamaglutenase - Takeda

Alternative Names: Kuma-062; KumaMax; PvP-001; PvP-002; Synthetic enzymes - PvP Biologics; TAK-062

Latest Information Update: 04 Jul 2025

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At a glance

  • Originator University of Washington
  • Developer PvP Biologics
  • Class Anti-inflammatories; Digestion aids; Enzymes; Peptide hydrolases; Proteins; Recombinant proteins
  • Mechanism of Action Gliadin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Coeliac disease

Most Recent Events

  • 04 Jul 2025 Discontinued - Phase-II for Coeliac disease (In adolescents, In the elderly, In adults) in USA (PO) (Takeda pipeline, July 2025)
  • 06 Nov 2024 Takeda completes phase-II clinical trials in Coeliac disease (In adolescents, In adults, In the elderly) in USA (PO) (NCT05353985)
  • 30 Jun 2022 Phase-II clinical trials in Coeliac disease (In adolescents, In adults, In the elderly) in USA (PO) (NCT05353985)

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