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R 21

Drug Profile

R 21

Alternative Names: Malaria virus-like particle vaccine - MultiMalVax; Matrix-M; Plasmodium falciparum circumsporozoite protein/HBsAg subunit vaccine - Multimalvax; R21

Latest Information Update: 28 Oct 2019

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At a glance

  • Originator University of Oxford
  • Developer GlaxoSmithKline; University of Oxford
  • Class Antimalarials; Parasitic vaccines; Subunit vaccines; Virus-like particle vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Falciparum malaria

Most Recent Events

  • 28 Oct 2019 No recent reports of development identified for phase-I development in Falciparum-malaria(Prevention) in Burkina Faso (IM, Injection)
  • 06 Sep 2019 University of Oxford and Kenya Medical Research Institute plan a phase IIb trial for Falciparum malaria (Prevention, Combination therapy) in Kenya (IM, Injection), in January 2020 , (NCT03947190)
  • 01 Apr 2019 University of Oxford plans a phase Ib/IIb trial for Falciparum malaria (Prevention, In infants) in Burkina Faso, in May 2019 (NCT03896724)
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