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MK 4621

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Drug Profile

MK 4621

Alternative Names: ImOl 100; MK-4621; RGT 100; RGT100-PEI; RIG-I

Latest Information Update: 22 Feb 2022

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At a glance

  • Originator Rigontec
  • Developer Merck & Co; Rigontec
  • Class Antineoplastics; Gene therapies; Oligonucleotides; RNA
  • Mechanism of Action DDX58 protein stimulants; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Solid tumours

Most Recent Events

  • 22 Feb 2022 Discontinued - Phase-I for Solid tumours (Combination therapy, Late-stage disease, Recurrent) in Spain, Germany, France (Intratumoural)
  • 22 Feb 2022 Discontinued - Phase-I for Solid tumours (Late-stage disease, Recurrent) in France (Intratumoural)
  • 22 Feb 2022 Discontinued - Phase-I/II for Solid tumours (Late-stage disease, Recurrent) in United Kingdom, Germany, Spain (Intralesional)

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