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Fianlimab - Regeneron Pharmaceuticals

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Drug Profile

Fianlimab - Regeneron Pharmaceuticals

Alternative Names: Anti-LAG-3 antibody - Regeneron Pharmaceuticals; REGN-3767

Latest Information Update: 29 Aug 2024

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At a glance

  • Originator Regeneron Pharmaceuticals
  • Class Antineoplastics; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; CD223 antigen inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Malignant melanoma
  • Phase II/III Non-small cell lung cancer
  • Phase II Solid tumours
  • Phase I Haematological malignancies

Most Recent Events

  • 26 Aug 2024 Columbia University plans a phase II trial for Bladder cancer (Combination therapy) in USA (IV) (NCT06571708)
  • 21 Aug 2024 Phase I development is ongoing for Haematological malignancies (Late-stage disease, Combination therapy) in Australia, Ireland, South Korea, United Kingdom, USA (IV) (Regeneron pipeline, May 2024)
  • 19 Aug 2024 Phase-III clinical trials in Malignant melanoma (Combination therapy, Inoperable/Unresectable, Metastatic disease, Late-stage disease, First-line therapy) in USA (IV) (NCT06246916)

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