Olverembatinib - Ascentage Pharma
Alternative Names: APG 1351; BCR-ABL TKI; D 824; GZD 824; HQP 1351; IBI-348; OrebatinibLatest Information Update: 02 Dec 2024
Price :
$50 *
At a glance
- Originator Guangzhou Institutes of Biomedicine and Health
- Developer Ascentage Pharma; Innovent Biologics
- Class Antineoplastics; Benzamides; Fluorinated hydrocarbons; Piperazines; Pyrazoles; Pyridines; Small molecules
- Mechanism of Action Bcr-Abl tyrosine kinase inhibitors; Cytokine inhibitors; Fms-like tyrosine kinase 3 inhibitors; Proto-oncogene protein c-kit inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Chronic myeloid leukaemia
- Registered Acute myeloid leukaemia
- Phase III Precursor cell lymphoblastic leukaemia-lymphoma
- Phase I/II Gastrointestinal stromal tumours; Solid tumours
- Preclinical COVID 2019 infections; Renal cell carcinoma
Most Recent Events
- 21 Nov 2024 Efficacy and adverse events data from a phase I trial in Chronic myeloid leukaemia and Precursor cell lymphoblastic leukaemia-lymphoma released byAscentage Pharma
- 06 Nov 2024 Efficacy and adverse events data phase Ib trial in Chronic myeloid leukemia released by Ascentage , ,
- 13 Sep 2024 Efficacy data from a phase I/II trial in Solid tumors released by Ascentage Pharma