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Mufemilast - Tianjin Hemay Pharmaceutical

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Drug Profile

Mufemilast - Tianjin Hemay Pharmaceutical

Alternative Names: Hemay 005; Phosphodiesterase 4 (PDE4) inhibitors - Tianjin Hemay Biotech

Latest Information Update: 06 Jan 2026

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At a glance

  • Originator Tianjin Hemay Pharmaceutical
  • Developer Ganzhou Hemay Pharmaceutical; Tianjin Hemay Pharmaceutical
  • Class 2 ring heterocyclic compounds; Acetamides; Anti-inflammatories; Antipsoriatics; Ketones; Phenyl ethers; Pyrroles; Skin disorder therapies; Small molecules; Sulfones; Thiophenes
  • Mechanism of Action Type 4 cyclic nucleotide phosphodiesterase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Behcet's syndrome
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Plaque psoriasis
  • Phase III Behcet's syndrome
  • Phase II Ankylosing spondylitis; Atopic dermatitis; Ulcerative colitis
  • Phase I Chronic obstructive pulmonary disease; Psoriasis

Most Recent Events

  • 01 Jan 2026 Ganzhou Hemay Pharmaceutical plans a phase II trial for Chronic obstructive pulmonary disease in China (PO) (NCT07314242)
  • 30 Sep 2025 Registered for Plaque psoriasis in China (PO)
  • 03 Jun 2025 Anhui Hemay Pharmaceutical completes phase I trial in Chronic obstructive pulmonary disease (In volunteers) in China (PO) (NCT06908642)

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