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Naloxone/tianeptine - Tonix Pharmaceuticals

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Drug Profile

Naloxone/tianeptine - Tonix Pharmaceuticals

Alternative Names: Tianeptine; Tianeptine hemioxalate extended-release tablets; Tianeptine oxalate and naloxone controlled-release tablet - Tonix Pharmaceuticals; Tianeptine oxalate controlled-release - Tonix Pharmaceuticals; TNX 601; TNX-601 CR; TNX-601 ER

Latest Information Update: 02 Nov 2023

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At a glance

  • Originator Tonix Pharmaceuticals Holding Corp
  • Developer Rho; Tonix Pharmaceuticals Holding Corp
  • Class Antidotes; Anxiolytics; Benzofurans; Drug withdrawal therapies; Isoquinolines; Ketones; Morphinans; Nootropics; Small molecules; Thiazepines; Tricyclic antidepressants
  • Mechanism of Action Glutamate receptor modulators; Opioid mu receptor agonists; Opioid mu receptor antagonists; Peroxisome proliferator-activated receptor agonists; Serotonin uptake stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Cognition disorders; Major depressive disorder; Post-traumatic stress disorders

Most Recent Events

  • 31 Oct 2023 Discontinued - Phase-I for Cognition disorders in USA (PO)
  • 31 Oct 2023 Discontinued - Phase-I for Post-traumatic stress disorders (In volunteers) (PO)
  • 31 Oct 2023 Discontinued - Phase-II for Major depressive disorder (In the elderly, Monotherapy, In adults) in USA (PO)

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