Trans-resveratrol oral - Jupiter Orphan Therapeutics

Drug Profile

Trans-resveratrol oral - Jupiter Orphan Therapeutics

Alternative Names: JOT 101; JOT 102; JOT 104; JOT 105; JOT 106; JOTROL

Latest Information Update: 16 Mar 2018

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At a glance

  • Originator Jupiter Orphan Therapeutics
  • Developer Jupiter Orphan Therapeutics; Mayo Clinic; Murdoch Childrens Research Institute; Universidade de Coimbra
  • Class Antineoplastics; Antithrombotics; Cardiovascular therapies; Nonsteroidal anti-inflammatories; Phenols; Small molecules; Stilbenes; Vasodilators
  • Mechanism of Action Angiogenesis inhibitors; Antioxidants; Ribonucleotide reductase inhibitors; SIRT1 protein stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Friedreich's ataxia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alzheimer's disease; Friedreich's ataxia
  • Phase I Mucopolysaccharidosis I
  • Preclinical Pancreatic cancer; Spinocerebellar degeneration

Most Recent Events

  • 14 Mar 2018 Jupiter Orphan Therapeutics plans a pharmacokinetic, safety clinical trial in Mucopolysaccharidosis Type-I
  • 14 Mar 2018 Jupiter Orphan Therapeutics plans clinical trials in Friedreich's Ataxia and other mitochondrial dysfunction related diseases
  • 12 Mar 2018 Jupiter Orphan Therapeutics files an IND application with the US Food and Drug Administration in USA for Mucopolysaccharidosis Type-I
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