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Zalfermin

Drug Profile

Zalfermin

Alternative Names: NN 9500; NN9499; NNC-0194-0499

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator Novo Nordisk
  • Class Drug withdrawal therapies; Hepatoprotectants; Obesity therapies
  • Mechanism of Action Fibroblast growth factor receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-alcoholic steatohepatitis; Substance-related disorders
  • Phase I Non-alcoholic fatty liver disease
  • No development reported Obesity

Most Recent Events

  • 14 Mar 2025 Novo Nordisk completes a phase II trial in Non-alcoholic steatohepatitis (Combination therapy) in USA, Australia, Italy, Japan, South Korea, Poland, Singapore, Belgium, Bulgaria, Canada, Czech Republic, Denmark, France, Germany, Greece, India, Malaysia, Portugal, Puerto Rico, Russia, Spain, Taiwan, Turkey and United Kingdom (SC) (NCT05016882)
  • 30 Dec 2024 Novo Nordisk completes a phase I clinical trials in Non-alcoholic steatohepatitis (In volunteers) in Austria (SC) (NCT06188026)
  • 16 Dec 2024 Novo Nordisk completes a phase I pharmacokinetics trial (In volunteers) in Germany, Poland and Slovakia (SC) (NCT05917938)

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