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Macozinone - Ecole Polytechnique Federale de Lausanne/Nearmedic

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Drug Profile

Macozinone - Ecole Polytechnique Federale de Lausanne/Nearmedic

Alternative Names: PBTZ-169; PBTZ169 NCP

Latest Information Update: 28 Jan 2021

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At a glance

  • Originator A. N. Bach Institute of Biochemistry; Ecole Polytechnique Federale de Lausanne.
  • Developer NEARMEDIC
  • Class Antituberculars; Cyclohexanes; Fluorinated hydrocarbons; Nitrobenzenes; Piperazines; Thiazines
  • Mechanism of Action Cell wall inhibitors; DprE1 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Tuberculosis

Most Recent Events

  • 28 Jan 2021 No recent reports of development identified for phase-I development in Tuberculosis(In volunteers) in Switzerland (PO, Liquid)
  • 07 Sep 2020 Pharmacodynamics data from preclinical studies in Tuberculosis presented at the 30th Annual Congress of the European Respiratory Society (ERS-2020)
  • 12 Sep 2019 Chemical structure information added

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