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Safusidenib - AnHeart Therapeutics

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Drug Profile

Safusidenib - AnHeart Therapeutics

Alternative Names: AB-218; DS-1001; DS-1001b

Latest Information Update: 31 Oct 2024

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At a glance

  • Originator Daiichi Sankyo Company; National Cancer Center (Tokyo)
  • Developer AnHeart Therapeutics; Daiichi Sankyo Company; National Cancer Center (Tokyo)
  • Class Antineoplastics
  • Mechanism of Action Isocitrate dehydrogenase 1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Glioma
  • Phase I Cholangiocarcinoma; Solid tumours
  • No development reported Acute myeloid leukaemia; Chondrosarcoma

Most Recent Events

  • 18 Oct 2024 AnHeart Therapeutics terminates a phase I trials in Solid tumours and Cholangiocarcinoma (Late-stage disease, Metastatic disease, Second-line therapy or greater) in China (PO) (NCT05814536)
  • 13 Sep 2024 Efficacy data from a phase 0 trial in Glioma presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 10 Apr 2024 AnHeart Therapeutics has been acquired by Nuvation Bio

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