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Drug Profile

Isuzinaxib - AptaBio Therapeutics

Alternative Names: APX 115; EWHA-18278 Free base; Isuzinaxib hydrochloride - AptaBio Therapeutics

Latest Information Update: 20 Oct 2023

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At a glance

Originator AptaBio Therapeutics
Class Anti-inflammatories; Pyrazoles; Pyridines; Small molecules
Mechanism of Action NADPH oxidase inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Phase II Acute kidney injury; COVID 2019 infections; Diabetic nephropathies

Most Recent Events

12 Oct 2023 Efficacy data from a phase II trial in Diabetic nephropathies released by AptaBio Therapeutics
10 Oct 2023 Phase-II clinical trials in Acute kidney injury in South Korea (PO)
10 Oct 2023 Phase-II clinical trials in Acute kidney injury in USA (PO)

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