Research programme - natural killer cell therapeutics - Fate Therapeutics

Drug Profile

Research programme - natural killer cell therapeutics - Fate Therapeutics

Alternative Names: FT 500; FT 516; FT 819; FT500i; FT516i; hnCD16-iNK; iNK Cells; NcHaCD16-NKs

Latest Information Update: 22 May 2018

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At a glance

  • Originator Fate Therapeutics; University of Minnesota
  • Class Antineoplastics; Immunotherapies; Natural killer cell therapies
  • Mechanism of Action Cell replacements; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 16 May 2018 Fate Therapeutics in-licenses intellectual property covering new chimeric antigen receptor (CAR) constructs, off-the-shelf CAR-T cells, including the use of CRISPR and other technologies for development of FT 819 from Memorial Sloan Kettering Cancer Center
  • 16 May 2018 Fate Therapeutics owns an extensive intellectual property portfolio that broadly covers compositions and methods for the genome editing of iPSCs using CRISPR and other nucleases, including the use of CRISPR to insert a CAR in the TRAC locus for endogenous transcriptional control
  • 10 May 2018 Fate Therapeutics intends to file an IND with the US FDA for FT 500 for Solid tumours (Late-stage disease, Combination therapy) in the second quarter of 2018
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