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Zabedosertib - Bayer

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Drug Profile

Zabedosertib - Bayer

Alternative Names: BAY 1834845; IRAK-4 inhibitor - Bayer

Latest Information Update: 10 Oct 2025

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At a glance

  • Originator Bayer
  • Class Amides; Anti-inflammatories; Antipsoriatics; Antirheumatics; Fluorinated hydrocarbons; Indazoles; Organic sulfur compounds; Pyridines; Skin disorder therapies; Small molecules
  • Mechanism of Action IRAK4 protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atopic dermatitis
  • Preclinical Systemic lupus erythematosus
  • No development reported Pelvic inflammatory disorders; Psoriasis; Rheumatoid arthritis

Most Recent Events

  • 11 Jun 2025 Preclinical trials in Systemic lupus erythematosus in Germany (PO) prior to June 2025
  • 11 Jun 2025 Pharmacodynamics data from the preclinical trials in Systemic lupus erythematosus presented at the 26th Annual Congress of the European League Against Rheumatism 2025 (EULAR-2025)
  • 28 Jul 2024 No recent reports of development identified for phase-I development in Unspecified(In volunteers) in Netherlands (PO, Tablet)

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