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Teclistamab - Genmab/Janssen Research & Development

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Drug Profile

Teclistamab - Genmab/Janssen Research & Development

Alternative Names: BCMAxCD3 - Genmab/Janssen Research & Development; JNJ 7957; JNJ-64007957; Tebbei; Techvaili; teclistamab-cqyv; Tecvaili; TECVAYLI; Tekbeiri

Latest Information Update: 25 Sep 2025

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At a glance

  • Originator Genmab; Janssen Research & Development
  • Class Antineoplastics; Bispecific antibodies; Immunotherapies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Multiple myeloma

Most Recent Events

  • 19 Sep 2025 Updated efficacy and adverse events data from phase II MajesTEC-5 trial in Multiple myeloma released byJohnson and Johnson
  • 08 Aug 2025 Memorial Sloan-Kettering Cancer Center, Johnson & Johnson and Bristol-Myers Squibb initiate a phase I trial in Multiple myeloma (Second-line therapy or greater, Combination therapy) in USA (PO) (NCT07105059)
  • 01 Jul 2025 SpringWorks Therapeutics has been acquired by Merck KGaA

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