Anti BCMA CAR T cell therapy - Juno Therapeutics

Drug Profile

Anti BCMA CAR T cell therapy - Juno Therapeutics

Alternative Names: Anti-BCMA CAR - Juno Therapeutics; Anti-BMCA Chimeric antigen receptor cell therapy-Juno Therapeutics; BCMA-CAR-T-Juno Therapeutics; BCMA-specific CAR expressing T-Lymphocytes-Juno Therapeutics; BCMA-specific CAR-T-Juno Therapeutics; BCMA-Targeted CAR-T Cells-Juno Therapeutics; EGFRt/BCMA 41BBz CAR-T cell; ET 140; ET140 CAR; FCARH143; JCARH-125; MCARH171

Latest Information Update: 09 Mar 2018

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At a glance

  • Originator Juno Therapeutics
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Multiple myeloma

Most Recent Events

  • 06 Mar 2018 Juno Therapeutics has been acquired by Celgene Corporation
  • 01 Feb 2018 Phase-I/II clinical trials in Multiple myeloma (Second-line therapy or greater) in USA (IV) (NCT03430011)
  • 11 Dec 2017 Safety and efficacy data from a phase I trial in Multiple myeloma presented at the 59th Annual Meeting and Exposition of the American Society of Hematology (ASH-Hem-2017)
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