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Vimseltinib - Deciphera Pharmaceuticals

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Drug Profile

Vimseltinib - Deciphera Pharmaceuticals

Alternative Names: DCC 3014; DP-6865; ROMVIMZA

Latest Information Update: 19 Sep 2025

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At a glance

  • Originator Deciphera Pharmaceuticals
  • Developer Deciphera Pharmaceuticals; Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics; Pyrazoles; Pyridines; Pyrimidinones; Small molecules
  • Mechanism of Action Macrophage colony-stimulating factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Giant cell tumour of tendon sheath
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Giant cell tumour of tendon sheath
  • Phase II Graft-versus-host disease
  • Phase I/II Solid tumours
  • No development reported Sarcoma

Most Recent Events

  • 17 Sep 2025 Registered for Giant cell tumour of tendon sheath (Inoperable/Unresectable, Late-stage disease) in Liechtenstein, Iceland, Norway, European Union (PO)
  • 17 Sep 2025 Updated efficacy data from the phase-III MOTION trial in Giant cell tumour of tendon sheath released by Ono Pharmaceutical
  • 05 Sep 2025 Deciphera Pharmaceuticals plans a phase I pharmacokinetic trial in Healthy volunteers (PO) in November 2025 (NCT07158411)

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