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Vimseltinib - Deciphera Pharmaceuticals

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Drug Profile

Vimseltinib - Deciphera Pharmaceuticals

Alternative Names: DCC 3014; DP-6865

Latest Information Update: 13 Nov 2024

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At a glance

  • Originator Deciphera Pharmaceuticals
  • Developer Deciphera Pharmaceuticals; Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics; Pyrazoles; Pyridines; Pyrimidinones; Small molecules
  • Mechanism of Action Macrophage colony-stimulating factor receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Giant cell tumour of tendon sheath
  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Giant cell tumour of tendon sheath
  • Phase II Graft-versus-host disease
  • Phase I/II Solid tumours
  • No development reported Sarcoma

Most Recent Events

  • 01 Nov 2024 Phase-II clinical trials in Graft-versus-host disease (Treatment-resistant) in USA (PO) (NCT06619561)
  • 13 Sep 2024 Efficacy and adverse events data from the phase II expansion portion of a phase I/II trial in Giant cell tumor of tendon sheath presented at the 49th European Society for Medical Oncology Congress (ESMO-2024)
  • 19 Aug 2024 Preregistration for Giant cell tumour of tendon sheath (Inoperable/Unresectable, Late-stage disease) in USA (PO)

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