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LBS 007

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Drug Profile

LBS 007

Alternative Names: LBS-007

Latest Information Update: 03 Dec 2024

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At a glance

  • Originator Columbia University Medical Center; Memorial Sloan-Kettering Cancer Center
  • Developer Columbia University Medical Center; Lin Bioscience; Memorial Sloan-Kettering Cancer Center
  • Class Antineoplastics
  • Mechanism of Action CDC7 protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Precursor cell lymphoblastic leukaemia-lymphoma; Acute myeloid leukaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Acute myeloid leukaemia
  • Preclinical Haematological malignancies; Solid tumours

Most Recent Events

  • 27 Nov 2024 LBS 007 receives Fast Track designation for Acute myeloid leukaemia in USA
  • 27 Nov 2024 LBS 007 receives Orphan Drug status for Acute myeloid leukaemia in USA
  • 09 Dec 2023 Pharmacodynamics data from a preclinical trial in Acute myeloid leukaemia presented at the 65th American Society of Hematology Annual Meeting and Exposition 2023 (ASH-Hem-2023)

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