GSK 2696277

Drug Profile

GSK 2696277

Alternative Names: Autologous hematopoietic stem cells genetically modified with GLOBE lentiviral vector encoding for the human beta-globin gene

Latest Information Update: 15 Dec 2017

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At a glance

  • Originator Fondazione Telethon; GlaxoSmithKline; Ospedale San Raffaele
  • Class Gene therapies; Stem cell therapies
  • Mechanism of Action Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Phase II Beta-thalassaemia

Most Recent Events

  • 09 Dec 2017 Efficacy data from the phase I/II TIGET-BTHAL trial in Beta-thalassaemia presented at the 59th American Society of Hematology Annual Meeting (ASH-2017)
  • 04 Oct 2017 Phase-II clinical trials in Beta-thalassaemia (In children, In adolescents, In adults, In the elderly) in Italy (Intraosseous) (NCT03275051)
  • 12 Sep 2017 GlaxoSmithKline plans a phase II trial for Beta-thalassaemia (In children, In adults, In adolescents, In elderly) (Intraosseous) (NCT03275051)
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