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TRX E 002 1

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Drug Profile

TRX E 002 1

Alternative Names: Cantrixil; TRX-E-002-1; TRX1; TRXE002

Latest Information Update: 25 Apr 2025

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At a glance

  • Originator Novogen
  • Developer Kazia Therapeutics; Vivesto
  • Class Antineoplastics; Benzopyrans; Small molecules
  • Mechanism of Action Electron transport chain complex protein inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Ovarian cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Ovarian cancer
  • Preclinical Haematological malignancies
  • No development reported Fallopian tube cancer; Peritoneal cancer

Most Recent Events

  • 25 Apr 2025 Adverse events and pharmacodynamics data from preclinical trials in Haematological malignancies released by Vivesto
  • 19 Dec 2024 Vivesto files for patent protection for Cantrixil as a treatment for Haematological malignancies
  • 19 Dec 2024 Preclinical trials in Haematological malignancies in Sweden (unspecified route), prior to December 2024

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