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Doxycycline hyclate controlled release - POLYPID

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Drug Profile

Doxycycline hyclate controlled release - POLYPID

Alternative Names: D-PLEX; D-PLEX100; Doxycycline/polymer-lipid encapsulation matrix; PLEX-doxycycline

Latest Information Update: 19 Nov 2024

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At a glance

  • Originator POLYPID
  • Class Antibacterials; Collagenases; Skin disorder therapies; Tetracyclines
  • Mechanism of Action Protein 30S ribosomal subunit inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase III Surgical wound infections

Most Recent Events

  • 07 Nov 2024 Phase-III clinical trials in Surgical wound infections (Adjunctive treatment, In the elderly, Prevention, In adults) in Macedonia, Georgia, Bosnia-Herzegovina (Implant) (EudraCT2020-003617-36) (NCT04411199)
  • 07 Nov 2024 POLYPID initiates enrolment in a phase III SHIELD II trial in Surgical wound infections (Adjunctive treatment, In the elderly, Prevention, In adults) in USA, Hungary, Moldova, Romania (Implant) (EudraCT2020-003617-36) (NCT04411199)
  • 21 Oct 2024 Efficacy and adverse events data from a phase III SHIELD I trial in Surgical wound infections released by PolyPid

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