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Frevecitinib - Kinaset Therapeutics/Vectura

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Drug Profile

Frevecitinib - Kinaset Therapeutics/Vectura

Alternative Names: KN-002 - Kinaset Therapeutics/Vectura; VR-588

Latest Information Update: 24 Oct 2025

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At a glance

  • Originator Vectura
  • Developer Kinaset Therapeutics; Vectura
  • Class Anti-inflammatories; Antiasthmatics; Small molecules
  • Mechanism of Action Janus kinase 1 inhibitors; Janus kinase 2 inhibitors; Janus kinase 3 inhibitors; TRPV1 receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Asthma; Chronic obstructive pulmonary disease
  • No development reported Inflammation

Most Recent Events

  • 17 May 2025 Efficacy and pharmacodynamics data from phase Ib trial in Asthma presented at the 121st International Conference of the American Thoracic Society (ATS-2025)
  • 29 Jan 2025 The US FDA approves IND application for frevecitinib in Asthma
  • 07 Sep 2024 Adverse event and pharmacokinetics data from phase I trial in Asthma and Chronic-obstructive-pulmonary-disease presented at the 34th Annual Congress of the European Respiratory Society (ERS-2024)

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