Research programme: CAR-T cell based therapeutics - Autolus

Drug Profile

Research programme: CAR-T cell based therapeutics - Autolus

Alternative Names: Dominant negative SHP2 protein engineered CAR T-cells - Autolus; Engineered T-cell immunotherapeutics- Autolus

Latest Information Update: 03 Apr 2017

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At a glance

  • Originator University College London
  • Developer Autolus
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Multiple myeloma; T cell lymphoma

Most Recent Events

  • 22 Mar 2017 Pharmacodynamics data from preclinical trial in Multiple myeloma presented at the American Society of Hematology 58th Annual Meeting (ASH-Hem-2016)
  • 21 Mar 2017 CAR-T cell based therapeutics - Autolus is available for licensing as of 21 Mar 2017.
  • 04 Dec 2016 Preclinical trials in Multiple myeloma in United Kingdom (IV)
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