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Cotoretigene toliparvovec - Biogen

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Drug Profile

Cotoretigene toliparvovec - Biogen

Alternative Names: AAV XLRPGR; AAV-RPGR; AAV-RPGR-Gene-Therapy-NightstaRx; AAV-XLRPGR gene therapy; AAV8-RPGR; BIIB-112; NSR AAV-RPGR; NSR-RPGR

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Isis Innovation; University of Oxford
  • Developer Biogen
  • Class Eye disorder therapies; Gene therapies
  • Mechanism of Action Gene transference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Retinitis pigmentosa
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Retinitis pigmentosa

Most Recent Events

  • 23 Feb 2022 Discontinued - Phase-II/III for Retinitis pigmentosa in United Kingdom (Intraocular) (Biogen pipeline, February 2022)
  • 23 Feb 2022 Discontinued - Phase-II/III for Retinitis pigmentosa in USA (Intraocular) (Biogen pipeline, February 2022)
  • 14 May 2021 Interim efficacy and safety data from a phase II/III XIRIUS trial in Retinitis pigmentosa released by Biogen

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