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Class
Amides; Amines; Antineoplastics; Cyclohexanes; Ethers; Fluorinated hydrocarbons; Pyrazoles; Pyridines; Pyrimidines; Small molecules
Mechanism of Action
Proto oncogene protein c ret inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
Yes
-
Thyroid cancer; Non-small cell lung cancer
New Molecular Entity
Yes
Highest Development Phases
Marketed
Non-small cell lung cancer; Thyroid cancer
Phase II
Solid tumours
Most Recent Events
23 Feb 2023
Blueprint Medicines announces to regain global commercialization and development rights to pralsetinib excluding Greater China, following a decision by Roche to discontinue the collaboration agreement between the companies for Pralsetinib for strategic reasons
17 Jan 2023
Registered for Non-small cell lung cancer (Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Taiwan (PO)
17 Jan 2023
Registered for Thyroid cancer (Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in Taiwan (PO)
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