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Rezpegaldesleukin - Nektar Therapeutics

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Drug Profile

Rezpegaldesleukin - Nektar Therapeutics

Alternative Names: IL-2 conjugate; Interleukin-2 conjugate; LY-3471851; NKTR-358; PEG-conjugated rhIL-2; REZPEG - Nektar Therapeutics

Latest Information Update: 08 Mar 2025

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At a glance

  • Originator Nektar Therapeutics
  • Developer Eli Lilly and Company; Nektar Therapeutics
  • Class Anti-inflammatories; Antipsoriatics; Interleukins; Polyethylene glycols; Recombinant proteins; Skin disorder therapies
  • Mechanism of Action Interleukin 2 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Alopecia areata; Atopic dermatitis; Systemic lupus erythematosus
  • Discontinued Psoriasis; Ulcerative colitis

Most Recent Events

  • 26 Feb 2025 Nektar Therapeutics completes enrolment of patients in phase II REZOLVE-AA clinical trials in Alopecia areata in Poland, Canada and USA (SC) (NCT06340360)
  • 24 Feb 2025 Nektar Therapeutics plans a phase II trial for Type 1 diabetes mellitus
  • 10 Feb 2025 Nektar therapeutics receives fast track desgination for Atopic dermatitis in USA

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