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PI 2620

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Drug Profile

PI 2620

Alternative Names: [18F]PI-2620; PI-2620; Tau-PET tracer - AC Immune

Latest Information Update: 24 May 2024

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At a glance

  • Originator AC Immune
  • Developer AC Immune; Life Molecular Imaging; The Michael J. Fox Foundation for Parkinson's Research; University of Pennsylvania
  • Class 3-ring heterocyclic compounds; Fluorinated hydrocarbons; Imaging agents; Pyridines; Pyrroles; Radiopharmaceutical diagnostics
  • Mechanism of Action Positron-emission tomography enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Corticobasal degeneration; Progressive supranuclear palsy
  • New Molecular Entity No

Highest Development Phases

  • Phase III Alzheimer's disease; Dementia
  • Phase II Parkinson's disease; Progressive supranuclear palsy
  • Phase I Traumatic brain injuries

Most Recent Events

  • 10 May 2024 Life Molecular Imaging terminates the phase I trial in Traumatic brain injuries in USA (IV) (NCT05337774)
  • 05 Mar 2024 Life Molecular Imaging completes a phase-I clinical trial in Progressive supranuclear palsy (Diagnosis) in Germany (IV) (NCT05187546)
  • 28 Dec 2023 No recent reports of development identified for phase-I development in Alzheimer's-disease(Diagnosis) in Germany (IV, Injection)
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