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Tozorakimab - AstraZeneca

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Drug Profile

Tozorakimab - AstraZeneca

Alternative Names: MEDI-3506

Latest Information Update: 31 Dec 2024

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At a glance

  • Originator MedImmune
  • Developer AstraZeneca
  • Class Anti-inflammatories; Antiasthmatics; Antivirals; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin-33 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Chronic obstructive pulmonary disease; Respiratory insufficiency
  • Phase II Asthma
  • Discontinued Atopic dermatitis; COVID 2019 infections; Diabetic nephropathies

Most Recent Events

  • 16 Nov 2024 Adverse events data from a phase-II trial for Diabetic nephropathies presented at the American Heart Association Scientific Sessions 2024 (AHA-2024)
  • 09 Sep 2024 AstraZeneca completes a phase I pharmacokinetics trial (In volunteers) in Germany (SC) (NCT06304961)
  • 12 Aug 2024 Discontinued - Phase-I for Chronic obstructive pulmonary disease (In volunteers) in United Kingdom (IV)

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