Axitinib intravitreal implant - Ocular Therapeutix
Alternative Names: AXPAXLI; OTX-TKI; Tyrosine kinase inhibitor implantLatest Information Update: 10 Aug 2026
At a glance
- Originator Ocular Therapeutix
- Class Antineoplastics; Benzamides; Eye disorder therapies; Imidazoles; Indazoles; Pyridines; Small molecules
- Mechanism of Action Angiogenesis inhibitors; Platelet-derived growth factor beta receptor antagonists; Protein tyrosine kinase inhibitors; Proto-oncogene protein c-kit inhibitors; Vascular endothelial growth factor receptor-1 antagonists; Vascular endothelial growth factor receptor-2 antagonists; Vascular endothelial growth factor receptor-3 antagonists
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Orphan Drug Status
No
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity No
Highest Development Phases
- Phase III Diabetic retinopathy; Wet age-related macular degeneration
- Phase I Diabetic macular oedema
- No development reported Retinal vein occlusion
Most Recent Events
- 03 Aug 2026 Ocular Therapeutix scheduled its pre-NDA meeting with the US FDA for Q3 2026
- 17 Jun 2026 Ocular Therapeutix announces intention to launch Axitinib intravitreal implant for Wet age-related macular degeneration in 2027
- 29 Apr 2026 Ocular Therapeutix initiates enrolment in the phase IIIb SOL-X long-term extension trial for Wet-age related macular degeneration in USA (Intravitreous) (NCT07516132)