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Linaprazan glurate - Cinclus Pharma/Jiangsu Sinorda Biomedicine

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Drug Profile

Linaprazan glurate - Cinclus Pharma/Jiangsu Sinorda Biomedicine

Alternative Names: SND-001; X-842

Latest Information Update: 18 Jun 2026

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At a glance

  • Originator AstraZeneca
  • Developer Cinclus Pharma; Jiangsu Sinorda Biomedicine Co., Ltd; Shanghai Pharmaceutical Group
  • Class 2 ring heterocyclic compounds; Amines; Aminopyridines; Anti-inflammatories; Antibacterials; Antiulcers; Glutarates; Imidazoles; Pentanoic acids; Pyridines; Small molecules; Toluenes
  • Mechanism of Action Potassium-competitive acid blockers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Reflux oesophagitis
  • Phase III Erosive oesophagitis; Gastro-oesophageal reflux
  • Phase II Duodenal ulcer; Helicobacter infections

Most Recent Events

  • 03 Jun 2026 Updated efficacy data from the phase II LEED trial in Erosive oesophagitis released by Cinclus Pharma
  • 03 Jun 2026 Cinclus Pharma completes enrollment in the phase III HEEALING 1 trial in Gastro-oesophageal reflux in Europe (PO, Tablet)
  • 28 May 2026 Cinclus Pharma withdraws a phase III trial in Erosive oesophagitis due to strategic desicion by Sponsor (NCT07313774)

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