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Batoprotafib - Novartis

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Drug Profile

Batoprotafib - Novartis

Alternative Names: TNO-155

Latest Information Update: 06 Jun 2025

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At a glance

  • Originator Novartis
  • Developer Mirati Therapeutics; Novartis
  • Class Antineoplastics
  • Mechanism of Action Protein tyrosine phosphatase non receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Solid tumours
  • No development reported Colorectal cancer

Most Recent Events

  • 25 Apr 2025 Updated efficacy and adverse event data from a phase I trial in Non small cell lung cancer presented at the 116th Annual Meeting of the American Association for Cancer Research (AACR-2025)
  • 24 Feb 2025 Mirati Therapeutics in collaboration with Novartis completes a Phase-I/II clinical trials in Solid tumours (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in USA (PO) (NCT04330664)
  • 29 Feb 2024 Novartis withdraws a phase-I pharmacokinetic trial in Hepatic impairment (PO) prior to enrolment (NCT05490030)

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