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MEDI 5395

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Drug Profile

MEDI 5395

Alternative Names: MEDI-5395; Oncolytic Newcastle Disease Virus

Latest Information Update: 28 Mar 2025

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At a glance

  • Originator MedImmune
  • Developer AstraZeneca
  • Class Gene therapies; Immunotherapies; Oncolytic viruses
  • Mechanism of Action Advanced glycosylation end product modulators; Cell death stimulants; Granulocyte-macrophage colony-stimulating factor expression stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • No development reported Cancer; Solid tumours

Most Recent Events

  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Second-line therapy or greater) in United Kingdom (IV, Infusion)
  • 28 Mar 2025 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Second-line therapy or greater) in USA (IV, Infusion)
  • 10 Sep 2023 Pharmacokinetics data from a phase I trial in Solid tumours presented at the 2023 American College of Clinical Pharmacology Annual Meeting (ACCP-2023)

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