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Efocipegtrutide - Hanmi Pharmaceutical

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Drug Profile

Efocipegtrutide - Hanmi Pharmaceutical

Alternative Names: GLP-1/GIP/glucagon triagonist - Hanmi Pharmaceutical; HM-15211; LAPS-triple agonist

Latest Information Update: 27 Dec 2023

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At a glance

  • Originator Hanmi Pharmaceutical
  • Class Antidementias; Antifibrotics; Antihyperglycaemics; Antihyperlipidaemics; Antiparkinsonians; Hepatoprotectants; Obesity therapies; Peptides
  • Mechanism of Action Gastric inhibitory polypeptide receptor agonists; Glucagon like peptide 1 receptor agonists; Glucagon receptor agonists; HMG-CoA reductase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Primary sclerosing cholangitis; Idiopathic pulmonary fibrosis; Primary biliary cirrhosis
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Non-alcoholic steatohepatitis
  • Phase I Non-alcoholic fatty liver disease
  • Preclinical Hepatic fibrosis; Idiopathic pulmonary fibrosis
  • Discontinued Alzheimer's disease; Dyslipidaemias; Multiple sclerosis; Obesity; Parkinson's disease; Type 2 diabetes mellitus

Most Recent Events

  • 10 Nov 2023 Pharmacodynamics data from a preclinical trial in Liver Injury presented at the 74th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2023)
  • 21 Jun 2023 Pharmacodynamics data from a preclinical studies in Hepatic fibrosis presented at the European Association for the Study of the Liver Congress 2023 (EASL-2023)
  • 21 Jun 2023 Pharmacodynamics data from a preclinical studies in Non-alcoholic steatohepatitis presented at the European Association for the Study of the Liver Congress 2023 (EASL-2023)
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