Research programme: ICOS-CD28 dual agonists - Alpine Immune Sciences

Drug Profile

Research programme: ICOS-CD28 dual agonists - Alpine Immune Sciences

Alternative Names: dual ICOS/CD28 agonist; ICOSL vIgD; V-mAb localised ICOS/CD28 agonist; V-mAbs; vIgD localised ICOS/CD28 agonist

Latest Information Update: 08 Dec 2017

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At a glance

  • Originator Alpine Immune Sciences
  • Class Immunotherapies; Monoclonal antibodies; Proteins
  • Mechanism of Action CD28 antigen stimulants; Inducible T-cell co-stimulator protein agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Cancer

Most Recent Events

  • 06 Dec 2017 Pharmacodynamics data from a preclinical trial in Cancer released by Alpine Immune Sciences
  • 02 May 2017 Preclinical trials in Cancer in USA (unspecified route)
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