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Vornorexant - Taisho Pharmaceutical

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Drug Profile

Vornorexant - Taisho Pharmaceutical

Alternative Names: ORN-0829; TS-142

Latest Information Update: 01 Oct 2025

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At a glance

  • Originator Taisho Pharmaceutical
  • Class Fluorinated hydrocarbons; Oxazines; Pyrazoles; Pyridines; Sleep disorder therapies; Small molecules; Triazoles
  • Mechanism of Action Orexin receptor type 1 antagonists; Orexin receptor type 2 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Insomnia
  • No development reported Sleep apnoea syndrome

Most Recent Events

  • 25 Aug 2025 Preregistration for Insomnia in Japan (PO), prior to August 2025
  • 25 Aug 2025 Registered for Insomnia in Japan (PO)
  • 28 Mar 2024 No recent reports of development identified for phase-I development in Sleep-apnoea-syndrome(In the elderly, In adults) in Japan (PO, Tablet)

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