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Acoramidis - BridgeBio Pharma

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Drug Profile

Acoramidis - BridgeBio Pharma

Alternative Names: Acoramidis hydrochloride; AG-10; AG10 hydrochloride; ALXN 2060; Attruby; BBP-265; BEYONTTRA; Beyonttra

Latest Information Update: 20 Aug 2025

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At a glance

  • Originator Stanford University
  • Developer Alexion AstraZeneca Rare Disease; BridgeBio Pharma; Eidos Therapeutics
  • Class Benzoic acids; Ethers; Fluorobenzenes; Pyrazoles; Small molecules
  • Mechanism of Action Prealbumin modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Amyloidosis
  • New Molecular Entity Yes

Highest Development Phases

  • Registered Transthyretin-related hereditary amyloidosis

Most Recent Events

  • 11 Aug 2025 Eidos Therapeutics plans a phase III trial for Familial amyloid neuropathy and Transthyretin related hereditary amyloidosis (Treatment experienced ) (PO) in November 2025 (NCT07116473)
  • 19 May 2025 Updated efficacy data from the phase-III ATTRibute-CM trial in Transthyretin-related hereditary amyloidosis released by BridgeBio Pharma
  • 12 May 2025 Phase-III clinical trials in Transthyretin-related hereditary amyloidosis (Prevention) in Bulgaria, France, Germany, Italy, South Korea, Malaysia, Netherlands, Portugal, Singapore, Spain, Taiwan (PO) (NCT06563895)

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