M 8891
Alternative Names: M-8891Latest Information Update: 28 Jan 2023
At a glance
- Originator EMD Serono
- Developer EMD Serono; Merck KGaA
- Class Antineoplastics
- Mechanism of Action Methionine aminopeptidase 2 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- No development reported Solid tumours
Most Recent Events
- 28 Jan 2023 No recent reports of development identified for phase-I development in Solid-tumours(Combination therapy, Late-stage disease, Second-line therapy or greater) in USA (PO)
- 28 Jan 2023 No recent reports of development identified for phase-I development in Solid-tumours(Late-stage disease, Second-line therapy or greater) in USA (PO)
- 21 Mar 2022 EMD Serono and Merck terminated a phase I trial in Solid tumours (Late-stage disease, Second-line therapy or greater, Monotherapy, Combination therapy) in USA due to the next phase of internal development of the MetAP2 (M8891) program of company pipeline (NCT03138538)