SAGE 718

Drug Profile

SAGE 718

Alternative Names: SAGE-718

Latest Information Update: 13 Aug 2018

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At a glance

  • Originator SAGE Therapeutics
  • Class Small molecules
  • Mechanism of Action NMDA receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Smith-Lemli-Opitz syndrome
  • Preclinical Encephalitis

Most Recent Events

  • 07 Aug 2018 SAGE Therapeutics initiates a multiple ascending dose phase I trial in healthy volunteers before August 2018
  • 07 Aug 2018 SAGE Therapeutics plans clinical development in Central nervous system disorders subject to positive results from a multiple ascending dose phase I trial
  • 03 May 2018 Sage Therapeutics plans a phase I multiple ascending dose trial in volunteers in second quarter of 2018
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