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Encoberminogene rezmadenovec - Cornell University/Xylocor Therapeutics

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Drug Profile

Encoberminogene rezmadenovec - Cornell University/Xylocor Therapeutics

Alternative Names: AdVEGF-A116A+ gene therapy - XyloCor Therapeutics; AdVEGF-All6A+; AdVEGFXC1; XC-001

Latest Information Update: 10 Jan 2025

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At a glance

  • Originator Cornell University
  • Developer Cornell University; XyloCor Therapeutics
  • Class Gene therapies; Ischaemic heart disorder therapies; Vascular disorder therapies
  • Mechanism of Action Gene transference; Vascular endothelial growth factor replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Angina pectoris
  • Preclinical Coronary artery disease

Most Recent Events

  • 07 Jan 2025 Xylocor Therapeutics plans the phase II EXACT-2 trial for Refractory angina in 2025
  • 10 Jul 2024 Xylocor Therapeutics and SmartCella enters into license agreement for use of the extroducer infusion catheter system to administer encoberminogene rezmadenovec to the heart
  • 02 May 2024 Efficacy data from the phase I/II EXACT trial in Angina pectoris released by XyloCor Therapeutics

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