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JNJ 55308942

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Drug Profile

JNJ 55308942

Alternative Names: JNJ-55308942

Latest Information Update: 03 Dec 2025

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At a glance

  • Originator Janssen-Cilag
  • Class Anti-inflammatories; Antidepressants; Antiepileptic drugs; Behavioural disorder therapies; Neuropsychotherapeutics
  • Mechanism of Action Purinergic P2X7 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Bipolar depression
  • No development reported Epilepsy; Inflammation; Inflammatory bowel diseases; Mood disorders

Most Recent Events

  • 27 Jul 2025 Pharmacodynamics data from a preclinical trials in Inflammation presented at the Alzheimer's Association International Conference 2025 (AAIC-2025)
  • 12 Feb 2025 Janssen-Cilag International prematurely terminates a phase I pharmacokinetics trial (In volunteers) in Belgium, due to sponsor decision (CTIS2023-504055-27-00)
  • 17 May 2024 anssen Pharmaceutica completes a phase II trial in Bipolar depression in Canada (PO) (NCT05328297) (EUCT2021-004790-3)

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