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LY 3056480

Drug Profile

LY 3056480

Alternative Names: LY3056480

Latest Information Update: 29 Aug 2022

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At a glance

  • Originator Audion Therapeutics
  • Class Small molecules
  • Mechanism of Action Amyloid precursor protein secretase inhibitors; Notch signalling pathway inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Sensorineural hearing loss

Most Recent Events

  • 25 Aug 2022 Audion Therapeutics withdraws prior to enrolment a phase II VESTA trial in Sensorineural hearing loss (In adults, In the elderly) in USA (Intratympanic, Injection)(NCT05061758)
  • 30 Sep 2021 Audion Therapeutics plans the phase II VESTA trial for Sensorineural hearing loss (In adults, In the elderly) in USA (Intratympanic, Injection) in September 2022 (NCT05061758)
  • 28 Sep 2020 Phase I/II clinical trials ongoing in Sensorineural hearing loss (In adults, In the elderly) in Greece, Germany, United Kingdom (Intratympanic) (EudraCT2016-004544-10)

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