Pozelimab - Regeneron Pharmaceuticals
Alternative Names: Pozelimab-bbfg; REGN 3918; VeopozLatest Information Update: 20 Nov 2025
At a glance
- Originator Regeneron Pharmaceuticals
- Developer Alnylam Pharmaceuticals; Regeneron Pharmaceuticals
- Class Anti-inflammatories; Eye disorder therapies; Monoclonal antibodies
- Mechanism of Action Complement C5 inhibitors
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Orphan Drug Status
Yes - Paroxysmal nocturnal haemoglobinuria; Protein-losing enteropathy
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Protein-losing enteropathy
- Phase III Dry macular degeneration; Myasthenia gravis; Paroxysmal nocturnal haemoglobinuria
Most Recent Events
- 17 Nov 2025 Regeneron Pharmaceuticals plans a phase I trial for Dry macular degeneration (Intravitreous, Injection) in December 2025 (NCT07230834) (EudraCT2025-521758-40-00)
- 26 Aug 2025 Launched for Protein-losing enteropathy (In adults, In children, In the elderly, In infants, In adolescents) in USA (IV) prior to August 2025 (NCT07142343)
- 26 Aug 2025 Launched for Protein-losing enteropathy (In infants, In children, In the elderly, In adolescents, In adults) in USA (SC) prior to August 2025 (NCT07142343)