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ORP 101

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Drug Profile

ORP 101

Alternative Names: Buprenorphine dimer - OrphoMed; ORP-101

Latest Information Update: 06 Jan 2022

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At a glance

  • Originator OrphoMed
  • Class Cyclopropanes; Irritable bowel syndrome therapies; Morphinans; Opioid analgesics; Small molecules
  • Mechanism of Action Opioid kappa receptor antagonists; Opioid mu receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Irritable bowel syndrome

Most Recent Events

  • 04 Jan 2022 Safety and efficacy data from the phase II PREVAIL trial in Irritable bowel syndrome released by OrphoMed
  • 30 Nov 2021 OrphoMed completed phase II PREVAIL trial in Irritable bowel syndrome (In adults, In the elderly) in USA (PO, Tablet) by November 2021
  • 28 Feb 2021 No recent reports of development identified for phase-I development in Irritable-bowel-syndrome in USA (IV, Injection)

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