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Tamnorzatinib - Ono Pharmaceutical

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Drug Profile

Tamnorzatinib - Ono Pharmaceutical

Alternative Names: ONO 7475

Latest Information Update: 20 Jun 2024

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At a glance

  • Originator Ono Pharmaceutical
  • Developer Ono Pharmaceutical; University of Texas M. D. Anderson Cancer Center
  • Class Antineoplastics; Small molecules
  • Mechanism of Action Axl receptor tyrosine kinase inhibitors; Proto-oncogene protein c-mer inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Acute myeloid leukaemia
  • Phase I/II Myelodysplastic syndromes
  • Phase I Non-small cell lung cancer; Pancreatic cancer; Solid tumours

Most Recent Events

  • 05 Apr 2024 Pharmacodynamics and adverse events data from a phase I trial in Solid tumours presented at the 115th Annual Meeting of the American Association for Cancer Research AACR 2024
  • 06 Dec 2023 Phase-I clinical trials in Pancreatic cancer (Metastatic disease, Combination therapy, First-line therapy) in Japan (PO) (NCT06532331)
  • 15 Jun 2023 Tamnorzatinib is still in phase-I development in Solid-tumours(Late-stage disease, Metastatic disease, Combination therapy, Monotherapy) in Japan (PO, Tablet)

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