Either you have JavaScript disabled or your browser does not support Javascript . To work properly, this page requires JavaScript to be enabled.
How to enable JavaScript in your browser?

Quavonlimab - Merck Sharp & Dohme

Next Previous
Drug Profile

Quavonlimab - Merck Sharp & Dohme

Alternative Names: AK-107; MK-1308

Latest Information Update: 10 Oct 2025

Price :
$50 *
Note:
  • Adis is an information provider. We do not sell or distribute actual drugs.
  • Final gross price and currency may vary according to local VAT and billing address.
  • Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase.
  • A link to download a PDF version of the drug profile will be included in your email receipt.

At a glance

  • Originator Akeso Biopharma
  • Developer Merck Sharp & Dohme
  • Class Antineoplastics; Biological factors; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Liver cancer; Malignant melanoma; Non-small cell lung cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 25 Aug 2025 Merck Sharp & Dohme Corp completes the phase I/II KEYNOTE-U02 trial for Malignant melanoma (Combination therapy, Second-line therapy or greater, Late-stage disease, Inoperable/Unresectable) in USA, Switzerland, Australia, France, Germany, Israel, Italy, South Africa (IV) (NCT04305041) (EudraCT2019-003956-35)
  • 31 May 2024 Efficacy and adverse events data from a phase I/II KEYMAKER-U02A trial in Malignant melanoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 08 Apr 2024 Merck Sharp & Dohme completes the Phase-I/II clinical trials in Solid tumours (Combination therapy, Metastatic disease, Late-stage disease) in USA, Australia, Canada, Chile, France, Greece, Israel, Italy, Japan, New Zealand, Poland, South Korea, Spain, Sweden, South Africa (IV) (NCT03179436)

You need to be a logged in or subscribed to view this content

Request demo (opens in a new window)
If your organization or you do not have a subscription, try one of the following: If your organization has a subscription, there are several access options, even while working remotely:
  • Working within your organization’s network
  • with username/password or try to via your institution
  • Persisted access using your organization’s identifier stored in your user browser for 90 days
Back to top