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Quavonlimab - Merck Sharp & Dohme

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Drug Profile

Quavonlimab - Merck Sharp & Dohme

Alternative Names: AK-107; MK-1308

Latest Information Update: 04 Jul 2024

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At a glance

  • Originator Akeso Biopharma
  • Developer Merck Sharp & Dohme
  • Class Antineoplastics; Biological factors; Immunotherapies; Monoclonal antibodies
  • Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Liver cancer; Malignant melanoma; Non-small cell lung cancer
  • Phase I/II Solid tumours

Most Recent Events

  • 31 May 2024 Efficacy and adverse events data from a phase I/II KEYMAKER-U02A trial in Malignant melanoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology (ASCO-2024)
  • 08 Apr 2024 Merck Sharp & Dohme completes the Phase-I/II clinical trials in Solid tumours (Combination therapy, Metastatic disease, Late-stage disease) in USA, Australia, Canada, Chile, France, Greece, Israel, Italy, Japan, New Zealand, Poland, South Korea, Spain, Sweden, South Africa (IV) (NCT03179436)
  • 13 May 2021 Phase-II clinical trials in Liver cancer (Combination therapy) (IV) (Merck pipeline, May 2021)

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