Drug Profile
Quavonlimab - Merck Sharp & Dohme
Alternative Names: AK-107; MK-1308Latest Information Update: 24 Apr 2024
Price :
$50
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At a glance
- Originator Akeso Biopharma
- Developer Merck Sharp & Dohme
- Class Antineoplastics; Biological factors; Immunotherapies; Monoclonal antibodies
- Mechanism of Action Antibody-dependent cell cytotoxicity; Cytotoxic T-lymphocyte antigen 4 inhibitors; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Liver cancer; Malignant melanoma; Non-small cell lung cancer
- Phase I/II Solid tumours
Most Recent Events
- 08 Apr 2024 Merck Sharp & Dohme completes the Phase-I/II clinical trials in Solid tumours (Combination therapy, Metastatic disease, Late-stage disease) in USA, Australia, Canada, Chile, France, Greece, Israel, Italy, Japan, New Zealand, Poland, South Korea, Spain, Sweden, South Africa (IV) (NCT03179436)
- 13 May 2021 Phase-II clinical trials in Liver cancer (Combination therapy) (IV) (Merck pipeline, May 2021)
- 16 Feb 2021 Phase-I/II clinical trials in Malignant melanoma (Combination therapy, Metastatic disease, Late-stage disease, Inoperable/Unresectable, Second-line therapy or greater) in France (IV) (EudraCT2020-003742-36)