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ET 1402L1-CART

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Drug Profile

ET 1402L1-CART

Alternative Names: AFP-CAR; AFP/ET1402; anti-AFP-ARTEMIS®2; ET-140203; ET140202; ET1402L1; ET1402L1-ARTEMIS®; ET1402L1-ARTEMIS®2

Latest Information Update: 17 Apr 2024

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At a glance

  • Originator Eureka Therapeutics
  • Developer Eureka Therapeutics; First Affiliated Hospital-Xi'an Jiaotong University
  • Class Antineoplastics; CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer; Hepatoblastoma
  • New Molecular Entity No
  • Available For Licensing Yes - Liver cancer

Highest Development Phases

  • Phase I/II Liver cancer

Most Recent Events

  • 20 Jun 2023 Eureka Therapeutics terminates a phase I/II ARYA-1 trial in Liver cancer (Metastatic disease, Inoperable/Unresectable, Late-stage disease, Second-line therapy or greater) in USA (IV), to direct the efforts to the pediatric study ARYA-2 (NCT04502082)
  • 28 Mar 2023 No recent reports of development identified for phase-I development in Liver-cancer(Combination therapy, In the elderly, Late-stage disease, In adults) in China (IV, Infusion)
  • 28 Mar 2023 No recent reports of development identified for phase-I development in Liver-cancer(Metastatic disease, Second-line therapy or greater) in China (IV, Infusion)

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