Research programme: chimeric antigen receptor T cell therapies - CRISPR Therapeutics

Drug Profile

Research programme: chimeric antigen receptor T cell therapies - CRISPR Therapeutics

Alternative Names: Allogeneic CAR T-cell therapy - CRISPR Therapeutics; Anti-BCMA CAR-T cells - CRISPR Therapeutics; Anti-CD70 CAR-T cells - CRISPR Therapeutics; CRISPR-based CAR-T cell therapies - CRISPR Therapeutics; CTX 101 - CRISPR Therapeutics; CTX 110; CTX 120; CTX 130

Latest Information Update: 20 Apr 2018

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At a glance

  • Originator CRISPR Therapeutics
  • Class CAR-T cell therapies; Gene therapies; Immunotherapies
  • Mechanism of Action Immunologic cytotoxicity; T lymphocyte replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Preclinical Haematological malignancies; Solid tumours

Most Recent Events

  • 07 Aug 2018 CRISPR Therapeutics announces intention to submit IND application for CTX 110 for Haematological malignancies in late 2018
  • 16 Apr 2018 Preclinical trials in Solid tumours in Switzerland (Parenteral) before April 2018
  • 10 Nov 2017 CRISPR Therapeutics plans clinical development of CTX 110 for Haematological malignancies in early 2019
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