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N acetylcysteine amide - Nacuity Pharmaceuticals

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Drug Profile

N acetylcysteine amide - Nacuity Pharmaceuticals

Alternative Names: AT-001 - Arctic Therapeutics; NACA - Nacuity Pharmaceuticals; NPI-001

Latest Information Update: 07 Oct 2025

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At a glance

  • Originator Nacuity Pharmaceuticals
  • Developer Arctic Therapeutics; Nacuity Pharmaceuticals
  • Class Eye disorder therapies; Neuroprotectants; Small molecules; Sulfhydryl compounds
  • Mechanism of Action Antioxidants; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Retinitis pigmentosa
  • New Molecular Entity No

Highest Development Phases

  • Phase II Cerebral amyloid angiopathy
  • Phase I/II Cystinosis; Usher syndromes
  • Preclinical Retinitis pigmentosa

Most Recent Events

  • 02 Oct 2025 N acetylcysteine amide - Nacuity Pharmaceuticals receives Breakthrough Therapy status for Retinitis pigmentosa in USA
  • 21 Jul 2025 Arctic Therapeutics plans a phase IIa trial for Alzheimer’s disease in Denmark and Iceland (PO) (CTIS2024-519497-39-00)
  • 02 Apr 2025 Phase-II/III clinical trials in Cerebral amyloid angiopathy in Iceland (PO), prior to April 2025

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